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LAMA4

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known.
Full Name
laminin subunit alpha 4
Function
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Biological Process
Cell adhesionIEA:UniProtKB-KW
Negative regulation of cold-induced thermogenesisBy SimilarityISS:YuBioLab
Regulation of cell adhesionIEA:InterPro
Regulation of cell migrationIEA:InterPro
Regulation of embryonic developmentIEA:InterPro
Cellular Location
Secreted, extracellular space, extracellular matrix, basement membrane
Major component.
Involvement in disease
Cardiomyopathy, dilated 1JJ (CMD1JJ):
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
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Anti-LAMA4 antibodies

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Mouse Anti-LAMA4 Recombinant Antibody (CL3183) (CBMAB-L0548-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CL3183
Application*: WB, P
Datasheet SDS

Rat Anti-Lama4 Recombinant Antibody (CBYJL-2399) (CBMAB-L2712-YJ)

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Target: LAMA4
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJL-2399
Application*: IH
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (CBYJL-1095) (CBMAB-L0550-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1095
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (CL3185) (CBMAB-L0549-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CL3185
Application*: WB, P
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (839084) (CBMAB-L0546-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 839084
Application*: IC
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (CBYJL-1094) (CBMAB-L0545-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1094
Application*: E, IP, WB
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (CBYJL-1093) (CBMAB-L0544-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1093
Application*: C
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (CBYJL-1092) (CBMAB-L0543-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1092
Application*: E, C
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (5G8) (CBMAB-L0542-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5G8
Application*: P
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (CBYJL-1091) (CBMAB-L0541-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1091
Application*: WB
Datasheet SDS

Mouse Anti-LAMA4 Recombinant Antibody (CBYJL-1090) (CBMAB-L0540-YJ)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1090
Application*: IH, WB, IP, E
Datasheet SDS

Rabbit Anti-LAMA4 Recombinant Antibody (CBYJL-1089) (CBMAB-L0539-YJ)

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Target: LAMA4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1089
Application*: IC, IF
Datasheet SDS

Mouse Anti-LAMA4 Monoclonal Antibody (3H2) (CBMAB-1373-YC)

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Target: LAMA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H2
Application*: P, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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