LRIG1
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Full Name
leucine rich repeats and immunoglobulin like domains 1
Function
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Biological Process
Hair cycle processIEA:Ensembl
InnervationIEA:Ensembl
Otolith morphogenesisIEA:Ensembl
Sensory perception of soundIEA:Ensembl
InnervationIEA:Ensembl
Otolith morphogenesisIEA:Ensembl
Sensory perception of soundIEA:Ensembl
Cellular Location
Cell membrane
Topology
Extracellular: 35-794
Helical: 795-815
Cytoplasmic: 816-1093
Helical: 795-815
Cytoplasmic: 816-1093
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Anti-LRIG1 antibodies
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CompareTarget: LRIG1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1955
Application*: WB, IP, IF, E
Target: Lrig1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJL-2384
Application*: B
Target: LRIG1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1954
Application*: F
Target: LRIG1
Sensitivity: 0.024 ng/mL
Detection Range: 0.05-20 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: LRIG1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-794
Tag: His Tag
Target: LRIG1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-779
Tag: hFc Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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