LRRTM1

Diseases associated with LRRTM1 include Schizophrenia. Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. An important paralog of this gene is LRRTM2. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.

Full Name

Leucine Rich Repeat Transmembrane Neuronal 1

Function

Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.

Biological Process

Exploration behaviorIEA:Ensembl
Locomotory behaviorIEA:Ensembl
Long-term synaptic potentiationIEA:Ensembl
Negative regulation of receptor internalizationIEA:Ensembl
Positive regulation of synapse assemblyIEA:Ensembl
Protein localization to synapseIEA:Ensembl
Synapse organizationIEA:Ensembl

Cellular Location

Cell membrane
Cell junction, synapse, postsynaptic cell membrane

Topology

Extracellular: 35-427
Helical: 428-448
Cytoplasmic: 449-522

Anti-LRRTM1 antibodies

Mouse Anti-LRRTM1 Recombinant Antibody (CBYJL-2050) (CBMAB-L2173-YJ)

Datasheet

SDS

Target: LRRTM1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJL-2050

Application*: P

Mouse Anti-LRRTM1 Recombinant Antibody (CBYJL-2051) (CBMAB-L2174-YJ)

Datasheet

SDS

Target: LRRTM1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJL-2051

Application*: WB

Mouse Anti-LRRTM1 Recombinant Antibody (2C6) (CBMAB-L2175-YJ)

Datasheet

SDS

Target: LRRTM1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2C6

Application*: WB

Mouse Anti-LRRTM1 Recombinant Antibody (5C3) (CBMAB-L2176-YJ)

Datasheet

SDS

Target: LRRTM1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 5C3

Application*: WB

Mouse Anti-LRRTM1 Recombinant Antibody (5H9) (CBMAB-L2177-YJ)

Datasheet

SDS

Target: LRRTM1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 5H9

Application*: WB, IH

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)