LRRTM1
Diseases associated with LRRTM1 include Schizophrenia. Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. An important paralog of this gene is LRRTM2. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.
Full Name
Leucine Rich Repeat Transmembrane Neuronal 1
Function
Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.
Biological Process
Exploration behaviorIEA:Ensembl
Locomotory behaviorIEA:Ensembl
Long-term synaptic potentiationIEA:Ensembl
Negative regulation of receptor internalizationIEA:Ensembl
Positive regulation of synapse assemblyIEA:Ensembl
Protein localization to synapseIEA:Ensembl
Synapse organizationIEA:Ensembl
Locomotory behaviorIEA:Ensembl
Long-term synaptic potentiationIEA:Ensembl
Negative regulation of receptor internalizationIEA:Ensembl
Positive regulation of synapse assemblyIEA:Ensembl
Protein localization to synapseIEA:Ensembl
Synapse organizationIEA:Ensembl
Cellular Location
Cell membrane
Cell junction, synapse, postsynaptic cell membrane
Cell junction, synapse, postsynaptic cell membrane
Topology
Extracellular: 35-427
Helical: 428-448
Cytoplasmic: 449-522
Helical: 428-448
Cytoplasmic: 449-522
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Anti-LRRTM1 antibodies
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Target: LRRTM1
Sensitivity: 0.049 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: LRRTM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5H9
Application*: WB, IH
Target: LRRTM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5C3
Application*: WB
Target: LRRTM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2C6
Application*: WB
Target: LRRTM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-2051
Application*: WB
Target: LRRTM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-2050
Application*: P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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