LRRTM3

Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. An important paralog of this gene is LRRTM4. Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation (By similarity). LRRTM3 may play a role in the development and maintenance of the vertebrate nervous system.

Full Name

leucine rich repeat transmembrane neuronal 3

Function

Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation (By similarity).
May play a role in the development and maintenance of the vertebrate nervous system.

Biological Process

Positive regulation of amyloid-beta formationManual Assertion Based On ExperimentIMP:MGI
Positive regulation of synapse assemblyIEA:Ensembl
Presynapse assemblyManual Assertion Based On ExperimentIDA:SynGO

Cellular Location

Cell membrane
Cell junction, synapse, postsynaptic cell membrane
Localized to excitatory synapses.

Topology

Extracellular: 31-419
Helical: 420-440
Cytoplasmic: 441-581