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Mouse Anti-LRRTM3 Recombinant Antibody (CBYJL-2052) (CBMAB-L2179-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3). The antibody can be used for immunoassay techniques, such as IHC.
See all LRRTM3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-2052
Antibody Isotype
IgG2b
Application
IHC

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LRRTM3, Glu31-Lys419, Accession # Q86VH5.
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
leucine rich repeat transmembrane neuronal 3
Introduction
Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. An important paralog of this gene is LRRTM4. Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation (By similarity). LRRTM3 may play a role in the development and maintenance of the vertebrate nervous system.
Entrez Gene ID
347731
UniProt ID
Q86VH5
Alternative Names
Leucine Rich Repeat Containing 4B; Netrin-G3 Ligand; Leucine-Rich Repeats And Immunoglobulin-Like Domains 4; LRIG4; NGL-3; Leucine-Rich Repeat-Containing Protein 4B; HSM
Function
Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation (By similarity).
May play a role in the development and maintenance of the vertebrate nervous system.
Biological Process
Positive regulation of amyloid-beta formationManual Assertion Based On ExperimentIMP:MGI
Positive regulation of synapse assemblyIEA:Ensembl
Presynapse assemblyManual Assertion Based On ExperimentIDA:SynGO
Cellular Location
Cell membrane
Cell junction, synapse, postsynaptic cell membrane
Localized to excitatory synapses.
Topology
Extracellular: 31-419
Helical: 420-440
Cytoplasmic: 441-581
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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