MED6

MED6 (Mediator Complex Subunit 6) is a Protein Coding gene. Among its related pathways are Gene Expression and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). Gene Ontology (GO) annotations related to this gene include transcription factor binding and RNA polymerase II transcription cofactor activity.
Full Name
Mediator Complex Subunit 6
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Biological Process
Positive regulation of transcription by RNA polymerase II Source: MGI
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: GO_Central
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Stem cell population maintenance Source: Ensembl
Cellular Location
Nucleus
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Anti-MED6 antibodies

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Mouse Anti-MED6 Antibody (3D10) (CBMAB-0651-YC)

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Target: MED6
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3D10
Application*: IP, M
Datasheet SDS

MED6 Matched Antibody Pair (731) (APMAB-731LY)

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Target: MED6
Specificity: Human
Datasheet SDS

MED6 Matched Antibody Pair (730) (APMAB-730LY)

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Target: MED6
Specificity: Human
Datasheet SDS

MED6 Matched Antibody Pair (729) (APMAB-729LY)

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Target: MED6
Specificity: Human
Datasheet SDS

Mouse Anti-MED6 Recombinant Antibody (4C2) (CBMAB-A5378-LY)

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Target: MED6
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4C2
Application*: WB, E
Datasheet SDS

Mouse Anti-MED6 (AA 1-247) Recombinant Antibody (CBFYM-2014) (CBMAB-M2192-FY)

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Target: MED6
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-2014
Application*: WB
Datasheet SDS

Mouse Anti-MED6 Recombinant Antibody (CBFYM-2013) (CBMAB-M2191-FY)

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Target: MED6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-2013
Application*: E, WB
Datasheet SDS

Mouse Anti-MED6 Recombinant Antibody (CBFYM-2012) (CBMAB-M2190-FY)

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Target: MED6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2012
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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