Mouse Anti-MED6 Recombinant Antibody (4C2) (CBMAB-A5378-LY)

Name: Mouse Anti-MED6 Recombinant Antibody (4C2)
SKU: CBMAB-A5378-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

4C2

Application

WB, ELISA

Immunogen

MED6 (AAH04106, 1 a.a. ~ 246 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Mediator Complex Subunit 6

Entrez Gene ID

10001

UniProt ID

O75586

Alternative Names

NY-REN-28

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Biological Process

Positive regulation of transcription by RNA polymerase II Source: MGI
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: GO_Central
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Stem cell population maintenance Source: Ensembl

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

MED6 Matched Antibody Pair (729) (CAT#: APMAB-729LY)

MED6 Matched Antibody Pair (730) (CAT#: APMAB-730LY)

MED6 Matched Antibody Pair (731) (CAT#: APMAB-731LY)

Related Products

MED6 Matched Antibody Pair (729) (CAT#: APMAB-729LY)

Mouse Anti-MED6 Recombinant Antibody (CBFYM-2013) (CAT#: CBMAB-M2191-FY)

MED6 Matched Antibody Pair (731) (CAT#: APMAB-731LY)

MED6 Matched Antibody Pair (730) (CAT#: APMAB-730LY)

Mouse Anti-MED6 Recombinant Antibody (CBFYM-2012) (CAT#: CBMAB-M2190-FY)

Mouse Anti-MED6 Antibody (3D10) (CAT#: CBMAB-0651-YC)

Mouse Anti-MED6 (AA 1-247) Recombinant Antibody (CBFYM-2014) (CAT#: CBMAB-M2192-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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