MPRIP

MPRIP (Myosin Phosphatase Rho Interacting Protein) is a Protein Coding gene. Among its related pathways are Oncogenic MAPK signaling and HIV Life Cycle. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is TRIOBP.

Full Name

Myosin Phosphatase Rho Interacting Protein

Function

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

Biological Process

Actin filament organization Source: GO_Central

Cellular Location

Cytoskeleton
Note: Colocalizes with F-actin.

Anti-MPRIP antibodies

Mouse Anti-MPRIP Recombinant Antibody (CBFYM-2518) (CBMAB-M2705-FY)

Datasheet

SDS

Target: MPRIP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-2518

Application*: WB

Rabbit Anti-MPRIP Recombinant Antibody (D9I5T) (CBMAB-CP2274-LY)

Datasheet

SDS

Target: MPRIP

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: D9I5T

Application*: WB

Rabbit Anti-MPRIP Recombinant Antibody (D8G8R) (CBMAB-CP2275-LY)

Datasheet

SDS

Target: MPRIP

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: D8G8R

Application*: WB, IP

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)