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MTHFD1L

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
Full Name
Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1 Like
Function
May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2.
Biological Process
10-formyltetrahydrofolate biosynthetic process Source: BHF-UCL
Embryonic neurocranium morphogenesis Source: BHF-UCL
Embryonic viscerocranium morphogenesis Source: BHF-UCL
Folic acid-containing compound metabolic process Source: BHF-UCL
Formate metabolic process Source: BHF-UCL
Neural tube closure Source: BHF-UCL
Tetrahydrofolate interconversion Source: GO_Central
Cellular Location
Mitochondrion
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Anti-MTHFD1L antibodies

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Mouse Anti-MTHFD1L Recombinant Antibody (1E8) (CBMAB-A5661-LY)

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Target: MTHFD1L
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: 1E8
Application*: WB, E
Datasheet SDS

Rabbit Anti-MTHFD1L Recombinant Antibody (D8T7L ) (CBMAB-CP1597-LY)

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Target: MTHFD1L
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: D8T7L
Application*: WB
Datasheet SDS

Rabbit Anti-MTHFD1L Recombinant Antibody (D7O8E ) (CBMAB-CP1598-LY)

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Target: MTHFD1L
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D7O8E
Application*: WB, IP
Datasheet SDS

Mouse Anti-MTHFD1L (AA 801-900) Recombinant Antibody (CBFYM-2737) (CBMAB-M2930-FY)

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Target: MTHFD1L
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2737
Application*: WB
Datasheet SDS

Mouse Anti-MTHFD1L (AA 801-900) Recombinant Antibody (CBXF-1011) (CBMAB-F0309-CQ)

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Target: MTHFD1L
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-1011
Application*: E, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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