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NMD3

Ribosomal 40S and 60S subunits associate in the nucleolus and are exported to the cytoplasm. The protein encoded by this gene is involved in the passage of the 60S subunit through the nuclear pore complex and into the cytoplasm. Several transcript variants exist for this gene, but the full-length natures of only two have been described to date.

Full Name

NMD3 ribosome export adaptor

Function

Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.

Biological Process

Positive regulation of protein bindingManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of protein localization to nucleolusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of RNA biosynthetic processManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Protein transportIEA:UniProtKB-KW
Ribosomal large subunit export from nucleusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL

Cellular Location

Cytoplasm
Nucleus
Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.

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Anti-NMD3 antibodies

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Rabbit Anti-NMD3 Recombinant Antibody (CBWJN-1440) (CBMAB-N2717-WJ)

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Target: NMD3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBWJN-1440

Application*: WB, IP, P, IC

Mouse Anti-NMD3 Recombinant Antibody (A-5) (CBMAB-N2716-WJ)

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Target: NMD3

Host: Mouse

Specificity: Human

Clone: A-5

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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