NMD3
Ribosomal 40S and 60S subunits associate in the nucleolus and are exported to the cytoplasm. The protein encoded by this gene is involved in the passage of the 60S subunit through the nuclear pore complex and into the cytoplasm. Several transcript variants exist for this gene, but the full-length natures of only two have been described to date.
Full Name
NMD3 ribosome export adaptor
Function
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
Biological Process
Positive regulation of protein bindingManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of protein localization to nucleolusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of RNA biosynthetic processManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Protein transportIEA:UniProtKB-KW
Ribosomal large subunit export from nucleusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of protein localization to nucleolusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of RNA biosynthetic processManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Protein transportIEA:UniProtKB-KW
Ribosomal large subunit export from nucleusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Cellular Location
Cytoplasm
Nucleus
Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.
Nucleus
Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.
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Anti-NMD3 antibodies
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Target: NMD3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-1440
Application*: WB, IP, P, IC
Target: NMD3
Host: Mouse
Specificity: Human
Clone: A-5
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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