NMD3

Ribosomal 40S and 60S subunits associate in the nucleolus and are exported to the cytoplasm. The protein encoded by this gene is involved in the passage of the 60S subunit through the nuclear pore complex and into the cytoplasm. Several transcript variants exist for this gene, but the full-length natures of only two have been described to date.

NMD3 ribosome export adaptor

Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.

Positive regulation of protein bindingManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of protein localization to nucleolusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of RNA biosynthetic processManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Protein transportIEA:UniProtKB-KW
Ribosomal large subunit export from nucleusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL

Cytoplasm
Nucleus
Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.