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Rabbit Anti-NMD3 Recombinant Antibody (CBWJN-1440) (CBMAB-N2717-WJ)

This product is a Rabbit antibody that recognizes NMD3. The antibody CBWJN-1440 can be used for immunoassay techniques such as: WB, IP, IHC-P, ICC.
See all NMD3 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBWJN-1440
Antibody Isotype
IgG
Application
WB, IP, IHC-P, ICC

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NMD3 ribosome export adaptor
Introduction
Ribosomal 40S and 60S subunits associate in the nucleolus and are exported to the cytoplasm. The protein encoded by this gene is involved in the passage of the 60S subunit through the nuclear pore complex and into the cytoplasm. Several transcript variants exist for this gene, but the full-length natures of only two have been described to date. [provided by RefSeq, Feb 2016]
Entrez Gene ID
51068
UniProt ID
Q96D46
Alternative Names
NMD3 Ribosome Export Adaptor; HNMD3; 0S Ribosomal Export Protein NMD3; NMD3 Homolog (S. Cerevisiae); NMD3 Homolog; CGI-07;
Function
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
Biological Process
Positive regulation of protein bindingManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of protein localization to nucleolusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Positive regulation of RNA biosynthetic processManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Protein transportIEA:UniProtKB-KW
Ribosomal large subunit export from nucleusManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Cellular Location
Cytoplasm
Nucleus
Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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