PGGT1B

Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine. The enzyme is composed of a 48-kD alpha subunit and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.
Full Name
Protein Geranylgeranyltransferase Type I Subunit Beta
Function
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B.
Biological Process
Protein geranylgeranylationManual Assertion Based On ExperimentIDA:UniProtKB
Protein prenylationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
CAAX-protein geranylgeranyltransferase complex
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Anti-PGGT1B antibodies

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Mouse Anti-PGGT1B Recombinant Antibody (CBYC-P325) (CBMAB-P1577-YC)

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Target: PGGT1B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYC-P325
Application*: E, IC, WB
Datasheet SDS

Mouse Anti-PGGT1B Recombinant Antibody (5E4) (CBMAB-P1576-YC)

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Target: PGGT1B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5E4
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-PGGT1B Recombinant Antibody (CBLG1-3238) (CBMAB-G6446-LY)

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Target: PGGT1B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-3238
Application*: WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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