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PRSS12

This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. [provided by RefSeq]

Full Name

protease, serine, 12 (neurotrypsin, motopsin)

Function

Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.

Biological Process

ExocytosisISS:UniProtKB
Zymogen activationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Secreted

Involvement in disease

Intellectual developmental disorder, autosomal recessive 1 (MRT1):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.

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Anti-PRSS12 antibodies

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Mouse Anti-PRSS12 Recombinant Antibody (CBYC-P671) (CBMAB-P3058-YC)

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Target: PRSS12

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYC-P671

Application*: E, WB

Mouse Prss12 ELISA Kit (V2LY-0626-LY2775)

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Target: Prss12

Sensitivity: 0.021 ng/mL

Detection Range: 0.05-20 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Mouse

Assay Type: Sandwich

Reactivity: Mouse

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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