PSMD8

PSMD8 (Proteasome 26S Subunit, Non-ATPase 8) is a protein coding gene. Among its related pathways are Cell Cycle, Mitotic and RET signaling.

Proteasome 26S Subunit, Non-ATPase 8

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

Proteasome-mediated ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central

cytosol
nucleoplasm
nucleus
proteasome accessory complex
proteasome complex
proteasome regulatory particle
proteasome regulatory particle, lid subcomplex