PTGFRN
Predicted to be involved in myoblast fusion involved in skeletal muscle regeneration. Predicted to act upstream of or within lipid droplet organization. Located in cell surface.
Full Name
prostaglandin F2 receptor inhibitor
Function
Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity).
In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity).
In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity).
Biological Process
Lipid droplet organization
Myoblast fusion involved in skeletal muscle regeneration
Myoblast fusion involved in skeletal muscle regeneration
Cellular Location
Endoplasmic reticulum membrane
Golgi apparatus, trans-Golgi network membrane
Golgi apparatus, trans-Golgi network membrane
Topology
Extracellular: 26-832
Helical: 833-853
Cytoplasmic: 854-879
Helical: 833-853
Cytoplasmic: 854-879
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Anti-PTGFRN antibodies
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CompareTarget: PTGFRN
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-832
Tag: His Tag
Target: PTGFRN
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-830
Tag: His Tag
Target: PTGFRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4537
Application*: IH, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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