Mouse Anti-PTGFRN Recombinant Antibody (CBT4537) (V2LY-0625-LY1233)

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Basic Information

Host Animal
Mouse
Clone
CBT4537
Application
IHC, FC
Immunogen
Purified recombinant fragment of human CD315 (AA: extra 46-221) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
prostaglandin F2 receptor inhibitor
Entrez Gene ID
UniProt ID
Function
Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity).
In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity).
Biological Process
Lipid droplet organization
Myoblast fusion involved in skeletal muscle regeneration
Cellular Location
Endoplasmic reticulum membrane
Golgi apparatus, trans-Golgi network membrane
Topology
Extracellular: 26-832
Helical: 833-853
Cytoplasmic: 854-879
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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