PWWP3A

Enables nucleosome binding activity. Involved in DNA repair and chromatin organization. Located in cytosol and nucleoplasm.

Full Name

PWWP domain containing 3A, DNA repair factor

Research Area

Epigenetics and nuclear signaling; Cancer; Tags & cell markers

Function

Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

Biological Process

Chromatin organization
DNA repair

Cellular Location

Nucleus
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1

Anti-PWWP3A antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-PWWP3A Recombinant Antibody (CBT905) (V2LY-0625-LY3183)

Datasheet

SDS

Target: PWWP3A

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBT905

Application*: WB, P, IF, E

Rabbit Anti-PWWP3A Recombinant Antibody (D1Z6Y) (CBMAB-CP1611-LY)

Datasheet

SDS

Target: PWWP3A

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Monkey

Clone: D1Z6Y

Application*: WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)