PWWP3A

Enables nucleosome binding activity. Involved in DNA repair and chromatin organization. Located in cytosol and nucleoplasm.
Full Name
PWWP domain containing 3A, DNA repair factor
Research Area
Epigenetics and nuclear signaling; Cancer; Tags & cell markers
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Biological Process
Chromatin organization
DNA repair
Cellular Location
Nucleus
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1
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Anti-PWWP3A antibodies

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Mouse Anti-PWWP3A Recombinant Antibody (CBT905) (V2LY-0625-LY3183)

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Target: PWWP3A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT905
Application*: WB, P, IF, E
Datasheet SDS

Rabbit Anti-PWWP3A Recombinant Antibody (D1Z6Y) (CBMAB-CP1611-LY)

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Target: PWWP3A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: D1Z6Y
Application*: WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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