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Rabbit Anti-PWWP3A Recombinant Antibody (D1Z6Y) (CBMAB-CP1611-LY)


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Summary

Host Animal
Rabbit
Specificity
Human, Monkey
Clone
D1Z6Y
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg692 of human EXPAND1/MUM1 protein.
Specificity
Human, Monkey
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
PWWP domain containing 3A, DNA repair factor
Entrez Gene ID
Human84939
Monkey706727
UniProt ID
HumanQ2TAK8
MonkeyF6VGC0
Research Area
Epigenetics and nuclear signaling; Cancer; Tags & cell markers
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Biological Process
Chromatin organization
DNA repair
Cellular Location
Nucleus
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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