RASGRP3

The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]
Full Name
RAS Guanyl Releasing Protein 3
Function
Guanine nucleotide exchange factor (GEF) for Ras and Rap1.
Biological Process
Biological Process MAPK cascade1 PublicationNAS:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
guanyl-nucleotide exchange factor complex
integral component of plasma membrane
perinuclear region of cytoplasm
plasma membrane
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Anti-RASGRP3 antibodies

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Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: G7
Application*: IH, WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNR-249
Application*: E
Target: RASGRP3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Monkey
Clone: C33A3
Application*: WB
Target: RASGRP3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 8A29
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5D2
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5C5
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4G9
Application*: WB, IH
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3C5
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3B9
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G7
Application*: WB, IH
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C9
Application*: WB, P
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2C11
Application*: WB, IH
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1H4
Application*: E
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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