RASGRP3

The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]

Full Name

RAS Guanyl Releasing Protein 3

Function

Guanine nucleotide exchange factor (GEF) for Ras and Rap1.

Biological Process

Biological Process MAPK cascade1 PublicationNAS:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:UniProtKB

Cellular Location

guanyl-nucleotide exchange factor complex
integral component of plasma membrane
perinuclear region of cytoplasm
plasma membrane

Anti-RASGRP3 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-RASGRP3 Recombinant Antibody (G7) (CBMAB-R1514-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: G7

Application*: IH, WB

Mouse Anti-RASGRP3 Recombinant Antibody (CBCNR-249) (CBMAB-R1513-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBCNR-249

Application*: E

Rabbit Anti-RASGRP3 Recombinant Antibody (C33A3) (CBMAB-R1512-CN)

Datasheet

SDS

Target: RASGRP3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Monkey

Clone: C33A3

Application*: WB

Rabbit Anti-RASGRP3 Recombinant Antibody (8A29) (CBMAB-R1509-CN)

Datasheet

SDS

Target: RASGRP3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 8A29

Application*: WB

Mouse Anti-RASGRP3 Recombinant Antibody (5D2) (CBMAB-R1508-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5D2

Application*: WB

Mouse Anti-RASGRP3 Recombinant Antibody (5C5) (CBMAB-R1507-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5C5

Application*: WB

Mouse Anti-RASGRP3 Recombinant Antibody (4G9) (CBMAB-R1506-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 4G9

Application*: WB, IH

Mouse Anti-RASGRP3 Recombinant Antibody (3C5) (CBMAB-R1505-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 3C5

Application*: WB

Mouse Anti-RASGRP3 Recombinant Antibody (3B9) (CBMAB-R1504-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 3B9

Application*: WB

Mouse Anti-RASGRP3 Recombinant Antibody (2G7) (CBMAB-R1503-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2G7

Application*: WB, IH

Mouse Anti-RASGRP3 Recombinant Antibody (2C9) (CBMAB-R1502-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2C9

Application*: WB, P

Mouse Anti-RASGRP3 Recombinant Antibody (2C11) (CBMAB-R1501-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2C11

Application*: WB, IH

Mouse Anti-RASGRP3 Recombinant Antibody (1H4) (CBMAB-R1500-CN)

Datasheet

SDS

Target: RASGRP3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1H4

Application*: E

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)