RASGRP3
The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]
Full Name
RAS Guanyl Releasing Protein 3
Function
Guanine nucleotide exchange factor (GEF) for Ras and Rap1.
Biological Process
Biological Process MAPK cascade1 PublicationNAS:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
guanyl-nucleotide exchange factor complex
integral component of plasma membrane
perinuclear region of cytoplasm
plasma membrane
integral component of plasma membrane
perinuclear region of cytoplasm
plasma membrane
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Anti-RASGRP3 antibodies
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CompareTarget: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: G7
Application*: IH, WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNR-249
Application*: E
Target: RASGRP3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Monkey
Clone: C33A3
Application*: WB
Target: RASGRP3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 8A29
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5D2
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5C5
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4G9
Application*: WB, IH
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3C5
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3B9
Application*: WB
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G7
Application*: WB, IH
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C9
Application*: WB, P
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2C11
Application*: WB, IH
Target: RASGRP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1H4
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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