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Mouse Anti-RASGRP3 Recombinant Antibody (1H4) (CBMAB-R1500-CN)

This product is a Mouse antibody that recognizes RASGRP3. The antibody 1H4 can be used for immunoassay techniques such as: ELISA.
See all RASGRP3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1H4
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa. 1-99 from RASGRP3 (NP_733772) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RAS Guanyl Releasing Protein 3
Introduction
The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]
Entrez Gene ID
25780
UniProt ID
Q8IV61
Alternative Names
RAS Guanyl Releasing Protein 3; Calcium- And Diacylglycerol-Regulated Guanine Nucleotide Exchange Factor III; Calcium And DAG-Regulated Guanine Nucleotide Exchange Factor III; RAS Guanyl Releasing Protein 3 (Calcium And DAG-Regulated); Guanine Nucleotide Exchange Factor For Rap1; GRP3; Ras Guanyl-Releasing Protein 3; CalDAG-GEFIII; KIAA0846;
Function
Guanine nucleotide exchange factor (GEF) for Ras and Rap1.
Biological Process
Biological Process MAPK cascade1 PublicationNAS:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
guanyl-nucleotide exchange factor complex
integral component of plasma membrane
perinuclear region of cytoplasm
plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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