S100A3
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq]
Full Name
S100 calcium binding protein A3
Function
Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
Cellular Location
Cytoplasm
PTM
More than half of the arginine residues undergo citrullination by PAD1 and PAD2. Arg-51 is specifically citrullinated by PAD3 and promotes tetramerization.
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Anti-S100A3 antibodies
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Target: S100A3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1D4
Application*: WB, E
Target: S100A3
Host: Mouse
Specificity: Human
Clone: CBXS-2006
Application*: WB, IP, IF, E
Target: S100A3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-1134
Application*: E
Target: S100A3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-1042
Application*: E
Target: S100A3
Host: Mouse
Specificity: Human
Clone: CBXS-0078
Application*: WB, IC, P, C, E
Target: S100A3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5581
Application*: E, WB
Target: S100A3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5124
Application*: E
Target: S100A3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-3988
Application*: E, WB
Target: S100A3
Expressed Host: E. coli
Sequence: Amino Acid: 1-101
Tag: His Tag
Target: S100A3
Expressed Host: E. coli
Sequence: Amino Acid: 1-101
Tag: His & MBP Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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