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Mouse Anti-S100A3 Recombinant Antibody (1D4) (CBMAB-A7860-LY)

The product is antibody recognizes S100A3. The antibody 1D4 immunoassay techniques such as: WB, ELISA.
See all S100A3 antibodies
Published Data
Fig. 1 Immunohistochemical staining of S100A3 in human HCC tissues.
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Fig. 2 Western blotting indicated the expression of S100A3 expressed in HepG2 cells and PHH.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
1D4
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
S100A3 (NP_002951, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
S100 calcium binding protein A3
Introduction
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq]
Entrez Gene ID
6274
UniProt ID
P33764
Alternative Names
S100E
Function
Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
Cellular Location
Cytoplasm
PTM
More than half of the arginine residues undergo citrullination by PAD1 and PAD2. Arg-51 is specifically citrullinated by PAD3 and promotes tetramerization.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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