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S100P

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer.

Full Name

S100 Calcium Binding Protein P

Function

May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

Biological Process

Biological Process endothelial cell migrationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process response to organic substanceManual Assertion Based On ExperimentIEP:UniProtKB

Cellular Location

Nucleus
Cytoplasm
Cell projection, microvillus membrane
Colocalizes with S100PBP in the nucleus. Colocolizes with EZR in the microvilli in a calcium-dependent manner.

Anti-S100P antibodies

Mouse Anti-S100P Recombinant Antibody (4E7) (CBMAB-A7879-LY)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 4E7

Application*: WB, E

Mouse Anti-S100P Recombinant Antibody (IHC658) (CBMAB-MA215-YC)

SDS

Target: S100P

Host: Mouse

Specificity: Human

Clone: IHC658

Application*: IH

Mouse Anti-S100P Recombinant Antibody (CBXS-3748) (CBMAB-S1021-CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXS-3748

Application*: IH

Mouse Anti-S100P Recombinant Antibody (CBXS-3812) (CBMAB-S1083-CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: CBXS-3812

Application*: WB, IF

Mouse Anti-S100P Recombinant Antibody (CBXS-4090) (CBMAB-S1347-CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4090

Application*: WB

Rabbit Anti-S100P Recombinant Antibody (CBXS-4256) (CBMAB-S1508-CQ)

SDS

Target: S100P

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBXS-4256

Application*: F

Mouse Anti-S100P Recombinant Antibody (CBXS-5049) (CBMAB-S2270-CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBXS-5049

Application*: E, IF, WB

Mouse Anti-S100P (AA 1-95) Recombinant Antibody (CBXS-0096) (CBMAB-S3095-CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXS-0096

Application*: E, WB

Mouse Anti-S100P Recombinant Antibody (CBXS-0097) (CBMAB-S3096-CQ)

SDS

Target: S100P

Host: Mouse

Specificity: Human

Clone: CBXS-0097

Application*: WB, IC, P, C, E

Mouse Anti-S100P Recombinant Antibody (CBXS-1795) (CBMAB-S4610-CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-1795

Application*: WB, IC

Mouse Anti-S100P Recombinant Antibody (CBXS-2661) (CBMAB-S5413-CQ)

SDS

Target: S100P

Host: Mouse

Specificity: Human

Clone: CBXS-2661

Application*: E, IF, WB

Mouse Anti-S100P Monoclonal Antibody (CBFYR-0041) (CBMAB-R0076-FY)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYR-0041

Application*: ELISA

Mouse Anti-S100P Recombinant Antibody (357517) (CBMAB-0795CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 357517

Application*: WB, IC

Mouse Anti-S100P Recombinant Antibody (1A4) (CBMAB-0796CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: 1A4

Application*: WB, IF

Mouse Anti-S100P Recombinant Antibody (4E7.) (CBMAB-0797CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 4E7.

Application*: WB, E, IF

Mouse Anti-S100P Recombinant Antibody (1A11) (CBMAB-0798CQ)

SDS

Target: S100P

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1A11

Application*: WB, E, IF

Rabbit Anti-S100P Recombinant Antibody (CBFYM-3116) (CBMAB-M3312-FY)

SDS

Target: S100P

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYM-3116

Application*: P

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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