loading...

SCARA5

SCARA5 (Scavenger Receptor Class A Member 5) is a Protein Coding gene. Among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity and ferritin receptor activity. An important paralog of this gene is MSR1.

Full Name

Scavenger Receptor Class A Member 5

Function

Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1).

Biological Process

Biological Process cellular iron ion homeostasisISS:UniProtKB
Biological Process cellular response to heatIEA:Ensembl
Biological Process endocytosisISS:UniProtKB
Biological Process iron ion transmembrane transportISS:UniProtKB
Biological Process protein homotrimerizationISS:UniProtKB

Cellular Location

Cell membrane

Topology

Cytoplasmic: 1-60
Helical: 61-81
Extracellular: 82-495

View more

Anti-SCARA5 antibodies

+ Filters

Loading...

Rat Anti-SCARA5 Recombinant Antibody (CBXS-3510) (CBMAB-S6239-CQ)

Compare

Target: SCARA5

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXS-3510

Application*: IH

Rat Anti-SCARA5 (AA 83-491) Recombinant Antibody (CBXS-0129) (CBMAB-S3120-CQ)

Compare

Target: SCARA5

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBXS-0129

Application*: IH

Mouse Anti-SCARA5 Recombinant Antibody (CBXS-1882) (CBMAB-S0132-CQ)

Compare

Target: SCARA5

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-1882

Application*: F

Human SCARA5 ELISA Kit (V2LY-0626-LY5205)

Compare

Target: SCARA5

Sensitivity: 0.0032 ng/mL

Detection Range: 0.007-1.5 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry