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Rat Anti-SCARA5 (AA 83-491) Recombinant Antibody (CBXS-0129) (CBMAB-S3120-CQ)

This product is a rat antibody that recognizes SCARA5. The antibody CBXS-0129 can be used for immunoassay techniques such as: IHC.
See all SCARA5 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBXS-0129
Antibody Isotype
IgG2a
Application
IHC

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 83-491

Target

Full Name
Scavenger Receptor Class A Member 5
Introduction
SCARA5 (Scavenger Receptor Class A Member 5) is a Protein Coding gene. Among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity and ferritin receptor activity. An important paralog of this gene is MSR1.
Entrez Gene ID
71145
UniProt ID
Q8K299
Alternative Names
4932433F15Rik; 4933425F03Rik; AV278087; Tesr
Function
Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1).
Biological Process
Biological Process cellular iron ion homeostasisISS:UniProtKB
Biological Process cellular response to heatIEA:Ensembl
Biological Process endocytosisISS:UniProtKB
Biological Process iron ion transmembrane transportISS:UniProtKB
Biological Process protein homotrimerizationISS:UniProtKB
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-60
Helical: 61-81
Extracellular: 82-495
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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