SDC3
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity.
Full Name
Syndecan 3
Function
Cell surface proteoglycan that may bear heparan sulfate (By similarity).
May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.
May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.
Biological Process
Cell migration
Cellular Location
Cell membrane
Topology
Extracellular: 1-387
Helical: 388-408
Cytoplasmic: 409-442
Helical: 388-408
Cytoplasmic: 409-442
PTM
O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules.
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Anti-SDC3 antibodies
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CompareTarget: SDC3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-3400
Application*: E, IC
Target: SDC3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1806
Application*: WB
Target: SDC3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1805
Application*: IC
Target: SDC3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1767
Application*: WB
Target: SDC3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1256
Application*: WB, IP
Target: SDC3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-0163
Application*: E, IC
Target: SDC3
Sensitivity: 0.0098 ng/mL
Detection Range: 0.02-6 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Sdc3
Sensitivity: 0.014 ng/mL
Detection Range: 0.03-9 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: SDC3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-311
Tag: His Tag
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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