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Rat Anti-SDC3 Recombinant Antibody (CBXS-1805) (CBMAB-S4617-CQ)


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Summary

Host Animal
Rat
Specificity
Human
Clone
CBXS-1805
Antibody Isotype
IgG2a
Application
ICC

Basic Information

Immunogen
NS0-derived recombinant human Syndecan-3, Gln48-Lys383, Accession # O75056
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Syndecan 3
Introduction
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity.
Entrez Gene ID
9672
UniProt ID
O75056
Alternative Names
Syndecan 3; Syndecan Proteoglycan 3; SYND3; Syndecan 3 (N-Syndecan); Syndecan Neural Type; N-Syndecan; Syndecan-3; KIAA0468; SDCN;
Function
Cell surface proteoglycan that may bear heparan sulfate (By similarity).
May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.
Biological Process
Cell migration
Cellular Location
Cell membrane
Topology
Extracellular: 1-387
Helical: 388-408
Cytoplasmic: 409-442
PTM
O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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