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SLC15A3

Full Name

solute carrier family 15, member 3

Function

Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (By similarity).
Also able to transport carnosine (PubMed:31073693).
Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).

Biological Process

Biological Process dipeptide import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process innate immune responseIEA:UniProtKB-KW
Biological Process ion transportTAS:Reactome
Biological Process peptidoglycan transportISS:UniProtKB
Biological Process positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathwayISS:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW

Cellular Location

Lysosome membrane
Endosome membrane

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Anti-SLC15A3 antibodies

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Mouse Anti-SLC15A3 Recombinant Antibody (5B4) (CBMAB-A8172-LY)

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Target: SLC15A3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Rat

Clone: 5B4

Application*: WB, E

Mouse Anti-SLC15A3 Recombinant Antibody (CBXS-3278) (CBMAB-S6018-CQ)

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Target: SLC15A3

Host: Mouse

Specificity: Human

Clone: CBXS-3278

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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