SLC15A3
Full Name
solute carrier family 15, member 3
Function
Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (By similarity).
Also able to transport carnosine (PubMed:31073693).
Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).
Also able to transport carnosine (PubMed:31073693).
Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).
Biological Process
Biological Process dipeptide import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process innate immune responseIEA:UniProtKB-KW
Biological Process ion transportTAS:Reactome
Biological Process peptidoglycan transportISS:UniProtKB
Biological Process positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathwayISS:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process innate immune responseIEA:UniProtKB-KW
Biological Process ion transportTAS:Reactome
Biological Process peptidoglycan transportISS:UniProtKB
Biological Process positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathwayISS:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Cellular Location
Lysosome membrane
Endosome membrane
Endosome membrane
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Anti-SLC15A3 antibodies
+ Filters

Target: SLC15A3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Rat
Clone: 5B4
Application*: WB, E
Target: SLC15A3
Host: Mouse
Specificity: Human
Clone: CBXS-3278
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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