Mouse Anti-SLC15A3 Recombinant Antibody (CBXS-3278) (CBMAB-S6018-CQ)

Name: Mouse Anti-SLC15A3 Recombinant Antibody (CBXS-3278)
SKU: CBMAB-S6018-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-3278

Application

ELISA, WB

Immunogen

SLC15A3 (NP_057666.1, 254aa-311aa) partial recombinant protein with GST tag

Specificity

Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 15, member 3

Entrez Gene ID

51296

UniProt ID

Q8IY34

Alternative Names

Solute Carrier Family 15 Member 3; Solute Carrier Family 15 (Oligopeptide Transporter), Member 3; Peptide/Histidine Transporter 2; Osteoclast Transporter; Peptide Transporter 3; OCTP; PHT2; PTR3; Solute Carrier Family 15, Member 3;

Function

Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (By similarity).
Also able to transport carnosine (PubMed:31073693).
Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).

Biological Process

Biological Process dipeptide import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process innate immune responseIEA:UniProtKB-KW
Biological Process ion transportTAS:Reactome
Biological Process peptidoglycan transportISS:UniProtKB
Biological Process positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathwayISS:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW

Cellular Location

Lysosome membrane
Endosome membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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