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Mouse Anti-SLC15A3 Recombinant Antibody (CBXS-3278) (CBMAB-S6018-CQ)

This product is a mouse antibody that recognizes SLC15A3. The antibody CBXS-3278 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC15A3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3278
Application
ELISA, WB

Basic Information

Immunogen
SLC15A3 (NP_057666.1, 254aa-311aa) partial recombinant protein with GST tag
Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 15, member 3
Entrez Gene ID
51296
UniProt ID
Q8IY34
Alternative Names
Solute Carrier Family 15 Member 3; Solute Carrier Family 15 (Oligopeptide Transporter), Member 3; Peptide/Histidine Transporter 2; Osteoclast Transporter; Peptide Transporter 3; OCTP; PHT2; PTR3; Solute Carrier Family 15, Member 3;
Function
Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (By similarity).
Also able to transport carnosine (PubMed:31073693).
Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).
Biological Process
Biological Process dipeptide import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process innate immune responseIEA:UniProtKB-KW
Biological Process ion transportTAS:Reactome
Biological Process peptidoglycan transportISS:UniProtKB
Biological Process positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathwayISS:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Cellular Location
Lysosome membrane
Endosome membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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