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SNCG

This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]
Full Name
Synuclein Gamma
Function
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity).
May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
Biological Process
Biological Process adult locomotory behaviorIEA:Ensembl
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein secretionIEA:Ensembl
Biological Process regulation of dopamine secretionIEA:Ensembl
Biological Process regulation of neuron deathManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of neurotransmitter secretionIEA:Ensembl
Biological Process synapse organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process synaptic vesicle endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, perinuclear region
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Cytoplasm, cytoskeleton, spindle
Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
PTM
Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases.
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Anti-SNCG antibodies

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Mouse Anti-SNCG Recombinant Antibody (CBXS-0610) (CBMAB-S3552-CQ)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0610
Application*: E, C, P, WB
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (CBT1178) (V2LY-0625-LY2968)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT1178
Application*: WB, P, IF, E
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (CBT4790) (V2LY-0625-LY2147)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4790
Application*: IH
Datasheet SDS

SNCG Matched Antibody Pair (1113) (APMAB-1113LY)

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Target: SNCG
Specificity: Human
Datasheet SDS

Rabbit Anti-SNCG Recombinant Antibody (CBXS-3527) (CBMAB-S6256-CQ)

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Target: SNCG
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBXS-3527
Application*: F, IC, IH, IP, WB
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (CBXS-0611) (CBMAB-S3553-CQ)

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Target: SNCG
Host: Mouse
Specificity: Human
Clone: CBXS-0611
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (CBXS-5486) (CBMAB-S2695-CQ)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5486
Application*: E, IH
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (CBXS-4435) (CBMAB-S1677-CQ)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4435
Application*: E, WB
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (CBXS-4206) (CBMAB-S1459-CQ)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4206
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (CBLG1-2441) (CBMAB-G6603-LY)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-2441
Application*: WB
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (514304) (CBMAB-G1189-LY)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 514304
Application*: WB
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (CBLNG-182) (CBMAB-1823-CN)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLNG-182
Application*: WB, IC, IH
Datasheet SDS

Mouse Anti-SNCG Recombinant Antibody (1H10D2) (CBMAB-1822-CN)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1H10D2
Application*: E, IH, P, WB
Datasheet SDS

Rabbit Anti-SNCG Antibody (11BA35) (CBMAB-1614CQ)

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Target: SNCG
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 11BA35
Application*: WB
Datasheet SDS

Mouse Anti-SNCG Antibody (11BA34) (CBMAB-1613CQ)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 11BA34
Application*: E, WB
Datasheet SDS

Mouse Anti-SNCG Antibody (11BA33) (CBMAB-1612CQ)

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Target: SNCG
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: 11BA33
Application*: E, WB
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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