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Mouse Anti-SNCG Recombinant Antibody (CBT1178) (V2LY-0625-LY2968)


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Tested Data
Mouse Anti-SNCG Recombinant Antibody (CBT1178) (V2LY-0625-LY2968) in IHC
Mouse Anti-SNCG Recombinant Antibody (CBT1178) (V2LY-0625-LY2968) in IHC
Mouse Anti-SNCG Recombinant Antibody (CBT1178) (V2LY-0625-LY2968) in WB
Mouse Anti-SNCG Recombinant Antibody (CBT1178) (V2LY-0625-LY2968) in WB

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT1178
Antibody Isotype
IgG
Application
WB, IHC-P, IF, ELISA

Basic Information

Immunogen
Purified recombinant fragment of Synuclein-γ expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
ELISA1:10,000
IHC1:200-1:1,000
WB1:500-1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Synuclein Gamma
Entrez Gene ID
6623
Function
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity).
May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
Biological Process
Biological Process adult locomotory behaviorIEA:Ensembl
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein secretionIEA:Ensembl
Biological Process regulation of dopamine secretionIEA:Ensembl
Biological Process regulation of neuron deathManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of neurotransmitter secretionIEA:Ensembl
Biological Process synapse organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process synaptic vesicle endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, perinuclear region
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Cytoplasm, cytoskeleton, spindle
Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
PTM
Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

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