SYNJ2BP

SYNJ2BP (Synaptojanin 2 Binding Protein) is a Protein Coding gene. Diseases associated with SYNJ2BP include Trench Fever. Gene Ontology (GO) annotations related to this gene include protein C-terminus binding and type II activin receptor binding. An important paralog of this gene is SYNJ2BP-COX16.Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.

Synaptojanin 2 Binding Protein

Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.

Biological Process cell-cell adhesionIBA:GO_Central1 Publication
Biological Process chemical synaptic transmissionIBA:GO_Central1 Publication
Biological Process establishment or maintenance of epithelial cell apical/basal polarityIBA:GO_Central1 Publication
Biological Process negative regulation of angiogenesisIMP:UniProtKB1 Publication
Biological Process negative regulation of endothelial cell migrationIMP:UniProtKB1 Publication
Biological Process negative regulation of endothelial cell proliferationIMP:UniProtKB1 Publication
Biological Process negative regulation of ERK1 and ERK2 cascadeIDA:UniProtKB1 Publication
Biological Process negative regulation of sprouting angiogenesisIMP:UniProtKB1 Publication
Biological Process protein targetingIEA:Ensembl
Biological Process receptor clusteringIBA:GO_Central1 Publication
Biological Process receptor localization to synapseIBA:GO_Central1 Publication
Biological Process regulation of endocytosisIEA:Ensembl
Biological Process regulation of Notch signaling pathwayIMP:UniProtKB1 Publication
Biological Process Rho protein signal transductionIEA:Ensembl

Mitochondrion outer membrane

Cytoplasmic: 1-117
Helical: 118-138
Mitochondrial intermembrane: 139-145