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Mouse Anti-SYNJ2BP Recombinant Antibody (CBXS-4756) (CBMAB-S1985-CQ)

This product is a mouse antibody that recognizes SYNJ2BP. The antibody CBXS-4756 can be used for immunoassay techniques such as: WB, FC.
See all SYNJ2BP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4756
Antibody Isotype
IgG1
Application
WB, FC

Basic Information

Immunogen
Recombinant full length human SYNJ2BP(NP_060843)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Synaptojanin 2 Binding Protein
Introduction
SYNJ2BP (Synaptojanin 2 Binding Protein) is a Protein Coding gene. Diseases associated with SYNJ2BP include Trench Fever. Gene Ontology (GO) annotations related to this gene include protein C-terminus binding and type II activin receptor binding. An important paralog of this gene is SYNJ2BP-COX16.Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
Entrez Gene ID
55333
UniProt ID
P57105
Alternative Names
ARIP2; OMP25
Function
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
Biological Process
Biological Process cell-cell adhesionIBA:GO_Central1 Publication
Biological Process chemical synaptic transmissionIBA:GO_Central1 Publication
Biological Process establishment or maintenance of epithelial cell apical/basal polarityIBA:GO_Central1 Publication
Biological Process negative regulation of angiogenesisIMP:UniProtKB1 Publication
Biological Process negative regulation of endothelial cell migrationIMP:UniProtKB1 Publication
Biological Process negative regulation of endothelial cell proliferationIMP:UniProtKB1 Publication
Biological Process negative regulation of ERK1 and ERK2 cascadeIDA:UniProtKB1 Publication
Biological Process negative regulation of sprouting angiogenesisIMP:UniProtKB1 Publication
Biological Process protein targetingIEA:Ensembl
Biological Process receptor clusteringIBA:GO_Central1 Publication
Biological Process receptor localization to synapseIBA:GO_Central1 Publication
Biological Process regulation of endocytosisIEA:Ensembl
Biological Process regulation of Notch signaling pathwayIMP:UniProtKB1 Publication
Biological Process Rho protein signal transductionIEA:Ensembl
Cellular Location
Mitochondrion outer membrane
Topology
Cytoplasmic: 1-117
Helical: 118-138
Mitochondrial intermembrane: 139-145
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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