Mouse Anti-SYNJ2BP Recombinant Antibody (CBXS-4756) (CBMAB-S1985-CQ)

Name: Mouse Anti-SYNJ2BP Recombinant Antibody (CBXS-4756)
SKU: CBMAB-S1985-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-4756

Application

WB, FC

Immunogen

Recombinant full length human SYNJ2BP(NP_060843)

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Synaptojanin 2 Binding Protein

Introduction

SYNJ2BP (Synaptojanin 2 Binding Protein) is a Protein Coding gene. Diseases associated with SYNJ2BP include Trench Fever. Gene Ontology (GO) annotations related to this gene include protein C-terminus binding and type II activin receptor binding. An important paralog of this gene is SYNJ2BP-COX16.Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.

Entrez Gene ID

55333

UniProt ID

P57105

Alternative Names

ARIP2; OMP25

Function

Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.

Biological Process

Biological Process cell-cell adhesionIBA:GO_Central1 Publication
Biological Process chemical synaptic transmissionIBA:GO_Central1 Publication
Biological Process establishment or maintenance of epithelial cell apical/basal polarityIBA:GO_Central1 Publication
Biological Process negative regulation of angiogenesisIMP:UniProtKB1 Publication
Biological Process negative regulation of endothelial cell migrationIMP:UniProtKB1 Publication
Biological Process negative regulation of endothelial cell proliferationIMP:UniProtKB1 Publication
Biological Process negative regulation of ERK1 and ERK2 cascadeIDA:UniProtKB1 Publication
Biological Process negative regulation of sprouting angiogenesisIMP:UniProtKB1 Publication
Biological Process protein targetingIEA:Ensembl
Biological Process receptor clusteringIBA:GO_Central1 Publication
Biological Process receptor localization to synapseIBA:GO_Central1 Publication
Biological Process regulation of endocytosisIEA:Ensembl
Biological Process regulation of Notch signaling pathwayIMP:UniProtKB1 Publication
Biological Process Rho protein signal transductionIEA:Ensembl

Cellular Location

Mitochondrion outer membrane

Topology

Cytoplasmic: 1-117
Helical: 118-138
Mitochondrial intermembrane: 139-145

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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