TCERG1
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Full Name
TCERG1 Gene(Protein Coding)
Transcription Elongation Regulator 1
Transcription Elongation Regulator 1
Function
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.
Biological Process
Biological Process mRNA processingIDA:ARUK-UCL1 Publication
Biological Process negative regulation of transcription by RNA polymerase IIIDA:BHF-UCL1 Publication
Biological Process negative regulation of transcription elongation by RNA polymerase IITAS:ARUK-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase IIIDA:ARUK-UCL1 Publication
Biological Process positive regulation of transcription elongation by RNA polymerase IITAS:ARUK-UCL1 Publication
Biological Process RNA splicingIDA:ARUK-UCL1 Publication
Biological Process negative regulation of transcription by RNA polymerase IIIDA:BHF-UCL1 Publication
Biological Process negative regulation of transcription elongation by RNA polymerase IITAS:ARUK-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase IIIDA:ARUK-UCL1 Publication
Biological Process positive regulation of transcription elongation by RNA polymerase IITAS:ARUK-UCL1 Publication
Biological Process RNA splicingIDA:ARUK-UCL1 Publication
Cellular Location
Nucleus
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Anti-TCERG1 antibodies
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Target: TCERG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: TCEAD79A
Application*: IF, WB, E
Target: TCERG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYJT-2242
Application*: E, F, IC, WB
Target: TCERG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2241
Application*: E, F, IC, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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