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Mouse Anti-TCERG1 Recombinant Antibody (TCEAD79A) (CBMAB-1830-CN)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
TCEAD79A
Antibody Isotype
IgG1
Application
IF, WB, ELISA

Basic Information

Immunogen
Recombinant fragment (Human)
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 1% BSA, pH 7.4
Preservative
0.05% Sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TCERG1 Gene(Protein Coding)


Transcription Elongation Regulator 1
Introduction
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. It is necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.
Entrez Gene ID
Human10915
Mouse56070
Rat307474
UniProt ID
HumanO14776
MouseQ8CGF7
RatD3ZTL0
Alternative Names
Urn1; CA150; TAF2S
Function
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.
Biological Process
Biological Process mRNA processingIDA:ARUK-UCL1 Publication
Biological Process negative regulation of transcription by RNA polymerase IIIDA:BHF-UCL1 Publication
Biological Process negative regulation of transcription elongation by RNA polymerase IITAS:ARUK-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase IIIDA:ARUK-UCL1 Publication
Biological Process positive regulation of transcription elongation by RNA polymerase IITAS:ARUK-UCL1 Publication
Biological Process RNA splicingIDA:ARUK-UCL1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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