TESMIN

Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may play a central role in the regulation of cell growth and differentiation and are involved in spermatogenesis. TESMIN is a metallothionein-like protein which has been shown to be expressed differentially in mouse testis and ovary.

Testis Expressed Metallothionein Like Protein

Essential for normal spermatogenesis and male fertility (By similarity).
Required for the completion of meiosis in male germ cells (By similarity).

Biological Process cell differentiationSource:UniProtKB-KW
Biological Process cellular metal ion homeostasisSource:UniProtKB1 Publication
Biological Process male meiotic nuclear divisionSource:UniProtKB
Biological Process regulation of DNA-templated transcriptionSource:GO_Central1 Publication
Biological Process response to metal ionSource:UniProtKB1 Publication
Biological Process spermatogenesisSource:UniProtKB

Cytoplasm
Nucleus
Predominantly localized to the cytoplasm. Translocates from the cytoplasm to the nucleus in the G2/M transition upon treatment with cadmium, cobalt or zinc.