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Mouse Anti-TESMIN Recombinant Antibody (CBYJT-2563) (CBMAB-T1722-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TESMIN (Testis Expressed Metallothionein Like Protein). The antibody can be used for immunoassay techniques, such as ELISA, ICC, IF, WB.
See all TESMIN antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2563
Antibody Isotype
IgG2a, κ
Application
ELISA, ICC, IF, WB

Basic Information

Immunogen
MTL5 (NP_004914, 399 a.a. ~ 508 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 399-508

Target

Full Name
Testis Expressed Metallothionein Like Protein
Introduction
Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may play a central role in the regulation of cell growth and differentiation and are involved in spermatogenesis. TESMIN is a metallothionein-like protein which has been shown to be expressed differentially in mouse testis and ovary.
Entrez Gene ID
9633
UniProt ID
Q9Y4I5
Alternative Names
Testis Expressed Metallothionein Like Protein; Metallothionein-Like 5, Testis-Specific (Tesmin); Testis-Specific Metallothionein-Like Protein; CXC Domain Containing 2; MTL5; Metallothionein-Like 5, Testis-Specific; CXCDC2; Tesmin; MTLT
Function
Essential for normal spermatogenesis and male fertility (By similarity).
Required for the completion of meiosis in male germ cells (By similarity).
Biological Process
Biological Process cell differentiationSource:UniProtKB-KW
Biological Process cellular metal ion homeostasisSource:UniProtKB1 Publication
Biological Process male meiotic nuclear divisionSource:UniProtKB
Biological Process regulation of DNA-templated transcriptionSource:GO_Central1 Publication
Biological Process response to metal ionSource:UniProtKB1 Publication
Biological Process spermatogenesisSource:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Predominantly localized to the cytoplasm. Translocates from the cytoplasm to the nucleus in the G2/M transition upon treatment with cadmium, cobalt or zinc.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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