TFF3
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq]
Full Name
trefoil factor 3 (intestinal)
Function
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
Biological Process
Biological Process maintenance of gastrointestinal epitheliumSource:GO_Central1 Publication
Biological Process regulation of glucose metabolic processSource:Ensembl
Biological Process regulation of glucose metabolic processSource:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
Cytoplasm
Cytoplasm
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Anti-TFF3 antibodies
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CompareTarget: TFF3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2685
Application*: WB, P, IC
Target: TFF3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: CBYJT-2693
Application*: P, WB
Target: TFF3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2692
Application*: WB, P
Target: TFF3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2691
Application*: IC, IH, IP, WB
Target: TFF3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2690
Application*: WB, IH
Target: TFF3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-2689
Application*: E, P, WB
Target: TFF3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2688
Application*: IC, PS, IP, WB
Target: TFF3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-2687
Application*: E, WB, P
Target: TFF3
Sensitivity: 0.022 ng/mL
Detection Range: 0.05-30 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Dog
Assay Type: Sandwich
Reactivity: Dog
Target: TFF3
Sensitivity: 0.017 ng/mL
Detection Range: 0.05-15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Cattle
Assay Type: Sandwich
Reactivity: Cattle
Target: TFF3
Sensitivity: 0.29 ng/mL
Detection Range: 0.5-200 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: TFF3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-94
Tag: His Tag
Target: TFF3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H7
Application*: SE, E
Target: TFF3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D9
Application*: WB, E
Target: TFF3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1D3G1
Application*: E, IH
Target: TFF3
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBYY-I1531
Application*: WB, IP, IF, E
Target: TFF3
Host: Mouse
Specificity: Human
Clone: CBFYH-2789
Application*: WB, IC, P, C, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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