Mouse Anti-TFF3 Recombinant Antibody (CBYJT-2690) (CBMAB-T1877-YJ)

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Basic Information

Host Animal
Mouse
Clone
CBYJT-2690
Application
WB, IHC
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human TFF3, Ala21-Phe80, Accession # Q07654
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 21-80
More Infomation

Target

Full Name
trefoil factor 3 (intestinal)
Introduction
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. TFF3 is expressed in goblet cells of the intestines and colon. TFF3 and two other related trefoil family member genes are found in a cluster on chromosome 21.
Entrez Gene ID
UniProt ID
Alternative Names
Trefoil Factor 3; Trefoil Factor 3 (Intestinal); Polypeptide P1.B; ITF; TFI; Intestinal Trefoil Factor; HP1.B; HITF; P1B
Function
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
Biological Process
Biological Process maintenance of gastrointestinal epitheliumSource:GO_Central1 Publication
Biological Process regulation of glucose metabolic processSource:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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