THBS2

THBS2 belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. It has been shown to play a role as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.

Thrombospondin 2

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.

Biological Process cell adhesionSource:UniProtKB-KW
Biological Process negative regulation of angiogenesisSource:UniProtKB1 Publication
Biological Process positive regulation of synapse assemblySource:Ensembl

basement membrane
collagen-containing extracellular matrix
extracellular region
platelet alpha granule

Intervertebral disc disease (IDD):
A common musculo-skeletal disorder caused by degeneration of intervertebral disks of the lumbar spine. It results in low-back pain and unilateral leg pain.