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Mouse Anti-THBS2 Recombinant Antibody (CBYJT-2941) (CBMAB-T2182-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to THBS2 (Thrombospondin 2). The antibody can be used for immunoassay techniques, such as WB.
See all THBS2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2941
Antibody Isotype
IgG2
Application
WB

Basic Information

Immunogen
Recombinant protein corresponding to human Thrombospondin-2
Specificity
Human
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Thrombospondin 2
Introduction
THBS2 belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. It has been shown to play a role as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.
Entrez Gene ID
7058
UniProt ID
P35442
Alternative Names
Thrombospondin 2; TSP2; Thrombospondin-2
Function
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.
Biological Process
Biological Process cell adhesionSource:UniProtKB-KW
Biological Process negative regulation of angiogenesisSource:UniProtKB1 Publication
Biological Process positive regulation of synapse assemblySource:Ensembl
Cellular Location
basement membrane
collagen-containing extracellular matrix
extracellular region
platelet alpha granule
Involvement in disease
Intervertebral disc disease (IDD):
A common musculo-skeletal disorder caused by degeneration of intervertebral disks of the lumbar spine. It results in low-back pain and unilateral leg pain.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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