TKTL2

TKTL2 (Transketolase Like 2) is a Protein Coding gene. Diseases related to TKTL2 include Nasopharyngitis. Among its related pathways are Pentose phosphate pathway and Carbon metabolism. Gene Ontology (GO) annotations related to TKTL2 include oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor and transketolase activity. An important paralog of TKTL2 is TKTL1.

transketolase-like 2

Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis.

Cytoplasm