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Mouse Anti-TKTL2 Recombinant Antibody (CBYJT-3279) (CBMAB-T2564-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3279
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa59-121 from human TKTL2 (NP_115512) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 59-121

Target

Full Name
transketolase-like 2
Introduction
TKTL2 (Transketolase Like 2) is a Protein Coding gene. Diseases related to TKTL2 include Nasopharyngitis. Among its related pathways are Pentose phosphate pathway and Carbon metabolism. Gene Ontology (GO) annotations related to TKTL2 include oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor and transketolase activity. An important paralog of TKTL2 is TKTL1.
Entrez Gene ID
84076
UniProt ID
Q9H0I9
Alternative Names
Transketolase Like 2; EC 2.2.1.1; Similar To Transketolase
Function
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis.
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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