TNRC6C

TNRC6C (Trinucleotide Repeat Containing 6C) is a Protein Coding gene. Among its related pathways are RET signaling and Innate Immune System. Gene Ontology (GO) annotations related to TNRC6C include RNA binding and nucleotide binding. An important paralog of TNRC6C is TNRC6A.

trinucleotide repeat containing 6C

Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.

Biological Process miRNA-mediated gene silencing Source:BHF-UCL1 Publication
Biological Process miRNA-mediated gene silencing by inhibition of translation Source:UniProtKB1 Publication
Biological Process positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Source:UniProtKB1 Publication
Biological Process positive regulation of nuclear-transcribed mRNA poly(A) tail shortening Source:UniProtKB1 Publication

cytosol
nucleoplasm
P-body