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TRMT61A

TRMT61A (TRNA Methyltransferase 61A) is a Protein Coding gene. Among its related pathways are Gene Expression and tRNA processing. Gene Ontology (GO) annotations related to this gene include tRNA (adenine-N1-)-methyltransferase activity.

Full Name

TRNA Methyltransferase 61A

Function

Catalytic subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508).
Catalytic subunit of mRNA N1-methyltransferase complex, which mediates methylation of adenosine residues at the N1 position of a small subset of mRNAs: N1 methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29107537, PubMed:29072297).

Biological Process

Biological Process mRNA methylation Source:UniProtKB2 Publications
Biological Process tRNA methylation Source:ComplexPortal1 Publication

Cellular Location

Nucleus

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Anti-TRMT61A antibodies

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Mouse Anti-TRMT61A Recombinant Antibody (C145I165) (CBMAB-C5976WJ)

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Target: TRMT61A

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: C145I165

Application*: DB

Mouse Anti-TRMT61A Recombinant Antibody (CBYY-C2031) (CBMAB-C3469-YY)

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Target: TRMT61A

Host: Mouse

Specificity: Human

Clone: CBYY-C2031

Application*: WB

Mouse Anti-TRMT61A Recombinant Antibody (CBYJT-4880) (CBMAB-T4426-YJ)

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Target: TRMT61A

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-4880

Application*: DB, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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