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Mouse Anti-TRMT61A Recombinant Antibody (C145I165) (CBMAB-C5976WJ)

This product is a Mouse antibody that recognizes TRMT61A. This antibody C145I165 can be used for immunoassay techniques such as: Dot.
See all TRMT61A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
C145I165
Antibody Isotype
IgG1
Application
Dot

Basic Information

Immunogen
C14orf172 antibody was raised in mouse using recombinant Human Chromosome 14 Open Reading Frame 172
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TRNA Methyltransferase 61A
Introduction
TRMT61A (TRNA Methyltransferase 61A) is a Protein Coding gene. Among its related pathways are Gene Expression and tRNA processing. Gene Ontology (GO) annotations related to this gene include tRNA (adenine-N1-)-methyltransferase activity.
Entrez Gene ID
115708
UniProt ID
Q96FX7
Alternative Names
TRNA Methyltransferase 61A; MRNA Methyladenosine-N(1)-Methyltransferase Catalytic Subunit TRMT61A; TRNA(M1A58)-Methyltransferase Subunit TRMT61A; TRNA(M1A58)MTase Subunit TRMT61A; C14orf172; TRM61; TRNA (Adenine(58)-N(1))-Methyltransferase Catalytic Subunit TRMT61A; TRNA (Adenine-N(1)-)-Methyltransferase Catalytic Subunit TRMT61A; TRNA (Adenine-N(1)-)-Methyltransferase Catalytic Subunit TRM61; TRNA Methyltransferase 61 Homolog A (S. Cerevisiae); TRNA(M1A58)-Methyltransferase Subunit TRM61;
Function
Catalytic subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508).
Catalytic subunit of mRNA N1-methyltransferase complex, which mediates methylation of adenosine residues at the N1 position of a small subset of mRNAs: N1 methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29107537, PubMed:29072297).
Biological Process
Biological Process mRNA methylation Source:UniProtKB2 Publications
Biological Process tRNA methylation Source:ComplexPortal1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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