UPK3B

UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[supplied by OMIM, Mar 2008]
Full Name
Uroplakin 3B
Function
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
Biological Process
Biological Process negative regulation of gene expression Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
Topology
Lumenal: 30-240
Helical: 241-266
Cytoplasmic: 267-320
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Anti-UPK3B antibodies

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Mouse Anti-UPK3B Recombinant Antibody (16k358) (CBMAB-C4711-CN)

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Target: UPK3B
Host: Mouse
Specificity: Cattle, Human, Pig, Rat
Clone: 16k358
Application*: IH, WB
Datasheet SDS

Mouse Anti-UPK3B Recombinant Antibody (CBT3765) (V2LY-0625-LY1831)

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Target: UPK3B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3765
Application*: F
Datasheet SDS

Mouse Anti-UPK3B Recombinant Antibody (CBT4660) (V2LY-0625-LY1830)

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Target: UPK3B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4660
Application*: IC, F
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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