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Mouse Anti-UPK3B Recombinant Antibody (16k358) (CBMAB-C4711-CN)

This product is a Mouse antibody that recognizes UPK3B. The antibody 16k358 can be used for immunoassay techniques such as: IHC, WB.
See all UPK3B antibodies

Summary

Host Animal
Mouse
Specificity
Cattle, Human, Pig, Rat
Clone
16k358
Application
IHC, WB

Basic Information

Immunogen
Asymmetric unit membrane (AUM) preparation from bovine urinary bladder
Specificity
Cattle, Human, Pig, Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.09% Sodium azide

Target

Full Name
Uroplakin 3B
Introduction
UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[supplied by OMIM, Mar 2008]
Entrez Gene ID
Human105375355
Pig100511685
Rat360790
Cattle282115
UniProt ID
HumanQ9BT76
PigF6Q8K1
RatQ566D0
CattleQ864V4
Alternative Names
Uroplakin 3B; Uroplakin IIIb; UPIIIB; UP3B; P35; Uroplakin-3b;
Function
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
Biological Process
Biological Process negative regulation of gene expression Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
Topology
Lumenal: 30-240
Helical: 241-266
Cytoplasmic: 267-320
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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