USF1

This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Full Name
USF1
Function
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Biological Process
Biological Process carbon catabolite regulation of transcription Source:BHF-UCL1 Publication
Biological Process cellular response to insulin stimulus Source:BHF-UCL1 Publication
Biological Process glucose homeostasis Source:BHF-UCL1 Publication
Biological Process late viral transcription Source:BHF-UCL1 Publication
Biological Process lipid homeostasis Source:BHF-UCL
Biological Process negative regulation of fibrinolysis Source:BHF-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:BHF-UCL2 Publications
Biological Process positive regulation of transcription from RNA polymerase II promoter by glucose Source:BHF-UCL1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:BHF-UCL1 Publication
Biological Process regulation of transcription from RNA polymerase II promoter by glucose Source:BHF-UCL1 Publication
Biological Process response to hypoxia Source:BHF-UCL1 Publication
Biological Process response to UV Source:BHF-UCL
Cellular Location
Nucleus
Involvement in disease
Hyperlipidemia, familial combined, 1 (FCHL1):
A disorder characterized by a variable pattern of elevated levels of serum total cholesterol, triglycerides or both. It is observed in a percentage of individuals with premature coronary heart disease.
View more

Anti-USF1 antibodies

+ Filters
Loading...
Target: USF1
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: G-2
Application*: WB, IP, IF, E
Target: USF1
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: B-9
Application*: WB, IP, IF, E
Target: USF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3F6
Application*: E, WB
Target: USF1
Host: Mouse
Specificity: Human
Clone: 2A7
Application*: E, WB
Target: USF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1264CT170.274.14
Application*: WB
Target: USF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C10
Application*: IP, E, WB
Target: USF1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1B8
Application*: IP, M
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.