Mouse Anti-USF1 Monoclonal Antibody (1B8) (CBMAB-0287-LY)

Name: Mouse Anti-USF1 Monoclonal Antibody (1B8)
SKU: CBMAB-0287-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1B8

Application

IP, MA

Immunogen

Recombinant peptide (Full Length)

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

USF1

Introduction

This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.

Entrez Gene ID

7391

UniProt ID

P22415

Alternative Names

bHLHb11; MLTFI; UEF

Function

Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.

Biological Process

Biological Process carbon catabolite regulation of transcription Source:BHF-UCL1 Publication
Biological Process cellular response to insulin stimulus Source:BHF-UCL1 Publication
Biological Process glucose homeostasis Source:BHF-UCL1 Publication
Biological Process late viral transcription Source:BHF-UCL1 Publication
Biological Process lipid homeostasis Source:BHF-UCL
Biological Process negative regulation of fibrinolysis Source:BHF-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:BHF-UCL2 Publications
Biological Process positive regulation of transcription from RNA polymerase II promoter by glucose Source:BHF-UCL1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:BHF-UCL1 Publication
Biological Process regulation of transcription from RNA polymerase II promoter by glucose Source:BHF-UCL1 Publication
Biological Process response to hypoxia Source:BHF-UCL1 Publication
Biological Process response to UV Source:BHF-UCL

Cellular Location

Nucleus

Involvement in disease

Hyperlipidemia, familial combined, 1 (FCHL1):
A disorder characterized by a variable pattern of elevated levels of serum total cholesterol, triglycerides or both. It is observed in a percentage of individuals with premature coronary heart disease.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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