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Mouse Anti-USF1 Monoclonal Antibody (1B8) (CBMAB-0287-LY)

This product is mouse monoclonal antibody recognizes USF1 of human. The antibody 1B8 immunoassay techniques such as: IP, MA.
See all USF1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B8
Antibody Isotype
IgG2b
Application
IP, MA

Basic Information

Immunogen
Recombinant peptide (Full Length)
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
USF1
Introduction
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Entrez Gene ID
7391
UniProt ID
P22415
Alternative Names
bHLHb11; MLTFI; UEF
Function
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Biological Process
Biological Process carbon catabolite regulation of transcription Source:BHF-UCL1 Publication
Biological Process cellular response to insulin stimulus Source:BHF-UCL1 Publication
Biological Process glucose homeostasis Source:BHF-UCL1 Publication
Biological Process late viral transcription Source:BHF-UCL1 Publication
Biological Process lipid homeostasis Source:BHF-UCL
Biological Process negative regulation of fibrinolysis Source:BHF-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:BHF-UCL2 Publications
Biological Process positive regulation of transcription from RNA polymerase II promoter by glucose Source:BHF-UCL1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:BHF-UCL1 Publication
Biological Process regulation of transcription from RNA polymerase II promoter by glucose Source:BHF-UCL1 Publication
Biological Process response to hypoxia Source:BHF-UCL1 Publication
Biological Process response to UV Source:BHF-UCL
Cellular Location
Nucleus
Involvement in disease
Hyperlipidemia, familial combined, 1 (FCHL1):
A disorder characterized by a variable pattern of elevated levels of serum total cholesterol, triglycerides or both. It is observed in a percentage of individuals with premature coronary heart disease.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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